When your skin needs regeneration, not just correction.
Polynucleotide treatments are an advanced approach to skin rejuvenation designed to support the skin’s natural repair and regenerative processes. Rather than adding volume or changing the structure of the face, polynucleotides work at a cellular level to support healthier looking skin, improve hydration and encourage collagen and elastin production.
At Mira Story Aesthetics, we offer a selection of polynucleotide treatments including Rejuran®, Nucleofill® and Nucleofill® Eyes. Each has a different formulation and treatment focus, allowing us to tailor your treatment to your skin’s individual needs – whether you’re looking to improve overall skin quality, address early signs of ageing or rejuvenate the delicate eye area.
Benefits of Polynucleotide Treatments
- Supports the skin’s natural regenerative processes
- Stimulates collagen and elastin production
- Improves overall skin quality
- Helps enhance hydration and elasticity
- Supports firmer, smoother-looking skin
- Helps improve the appearance of fine lines
- Can improve tired or dull-looking skin
- Helps refine skin texture
- Supports healthier-looking, more resilient skin
- Provides gradual, natural-looking rejuvenation
- Can be tailored to different areas of the face
- Specialised options are available for the delicate eye area
Our Polynucleotide Treatments
Rejuran® — Regenerative Skin Rejuvenation
Rejuran® is a polynucleotide-based injectable treatment designed to support the skin’s natural repair processes and improve overall skin quality. It works by supporting the skin’s regenerative environment, helping improve hydration, elasticity, texture and the appearance of fine lines over time.
It is particularly suited to clients looking for progressive improvements in skin quality rather than an immediate change in facial shape or volume.
Best for:
- Fine lines
- Dull or tired-looking skin
- Reduced elasticity
- Uneven texture
- Dehydrated skin
- Early signs of skin ageing
- Overall skin rejuvenation
Investment
Nucleofill® — Deep Skin Renewal & Firmness
Nucleofill® is a polynucleotide treatment designed to support skin regeneration, hydration and collagen stimulation. By working with the skin’s natural repair processes, it can help improve firmness, elasticity and overall skin quality.
Nucleofill® is suited to clients who want a gradual, natural-looking improvement in skin health and resilience without adding traditional filler volume.
Best for:
- Skin laxity
- Reduced firmness
- Fine lines
- Dehydration
- Poor skin quality
- Loss of elasticity
- Overall facial rejuvenation
Investment
Nucleofill® Eyes — Rejuvenation for the Delicate Eye Area
The skin around the eyes is thinner and more delicate than the rest of the face, making it particularly susceptible to fine lines, dehydration and loss of elasticity. Nucleofill® Eyes is specifically designed for this delicate area, supporting skin quality and regeneration while helping create a fresher, more rested-looking appearance.
The treatment focuses on improving the quality of the skin rather than adding volume, making it a considered option for clients who want subtle rejuvenation around the eyes.
Best for:
- Fine lines around the eyes
- Dehydrated eye-area skin
- Reduced elasticity
- Crepey texture
- Tired-looking eye area
- Early signs of ageing
Investment
Targeted Regeneration, Personalised to Your Skin
Polynucleotide treatments share a regenerative approach, but each product is formulated and positioned differently. Your clinician will assess your skin and recommend the most appropriate option for your concerns.
Regeneration Over Correction.
Polynucleotides represent a different philosophy of aesthetic treatment. Instead of simply filling lines or replacing lost volume, they focus on supporting the skin’s own regenerative processes. The result is gradual improvement in skin quality, rather than an obvious change in facial structure.
At Mira Story Aesthetics, we select treatments based on what your skin actually needs. Your clinician considers hydration, elasticity, texture, firmness and the areas you’d like to improve before recommending the most suitable polynucleotide treatment. Our approach is designed around progressive, natural-looking results that allow your skin to look healthier rather than simply “treated.”
Your Patient Journey
Your Consultation
Your treatment begins with a detailed assessment of your skin. Your clinician evaluates texture, hydration, elasticity, fine lines, firmness and overall skin quality before discussing your concerns and desired outcome. We then recommend the most appropriate polynucleotide and treatment plan.
Your Treatment
The selected polynucleotide is administered through a series of precise, superficial injections into the appropriate treatment areas. Treatment time varies depending on the product and area being treated. Comfort is prioritised throughout the procedure.
Your Aftercare
Small bumps, redness, swelling or tenderness can occur at the injection points immediately after treatment. These usually settle naturally. Your clinician will provide personalised aftercare instructions and advise you on skincare, exercise, heat exposure and other activities following your treatment.
Polynucleotides FAQ
What are polynucleotides?
Polynucleotides are injectable bioregenerative treatments designed to support the skin’s natural repair and regenerative processes. They are used primarily to improve skin quality rather than add facial volume.
How do polynucleotides work?
Polynucleotide treatments are designed to support the skin’s regenerative environment and stimulate processes associated with collagen and elastin production. Over time, this can help improve hydration, elasticity, firmness and overall skin quality.
Are polynucleotides the same as dermal filler?
No. Dermal fillers are primarily used to restore or add volume and provide structural support. Polynucleotides are focused on improving the quality and condition of the skin without being designed to significantly change facial volume.
What is Rejuran®?
Rejuran® is a polynucleotide-based injectable treatment designed to support skin regeneration and improve overall skin quality. It can help address concerns such as fine lines, dehydration, reduced elasticity and uneven texture.
What is Nucleofill®?
Nucleofill® is a polynucleotide treatment focused on supporting skin regeneration, hydration, firmness and elasticity. It is designed to create progressive improvements in skin quality and resilience.
What is Nucleofill® Eyes?
Nucleofill® Eyes is a treatment specifically intended for the delicate eye area. It focuses on improving skin quality, hydration and elasticity around the eyes while supporting a fresher, more rested appearance.
Which polynucleotide is best for the eyes?
Nucleofill® Eyes is specifically designed for the delicate eye area and may be recommended for clients concerned with fine lines, dehydration or reduced elasticity around the eyes. Your clinician will assess your individual anatomy and concerns first.
Canpolynucleotides improve finelines?
They may help improve the appearance of fine lines by supporting skin hydration, elasticity, and collagen production. Results develop progressively rather than creating an immediate filling effect.
Can polynucleotides tighten the skin?
Polynucleotides can support improvements in skin firmness and elasticity, particularly where reduced skin quality contributes to a less firm appearance. They are not a replacement for surgical lifting or treatments designed specifically for significant laxity.
When will I see results?
Some clients notice improvements in hydration and overall skin appearance relatively early, while more significant changes in firmness and skin quality develop progressively as the regenerative process takes place.
Howmanytreatmentswill I need?
The recommended number varies depending on the product, skin condition, and treatment goals. Some clients may benefit from a course of treatments for more comprehensive skin rejuvenation. Your clinician will create an individual treatment plan.
How long do results last?
Results vary according to the treatment, skin condition, lifestyle and individual response. Maintenance treatments may be recommended to support long-term skin quality.
How much does Rejuran® cost?
Rejuran® is priced at £280 for 2ml or £500 for 4ml.
How much does Nucleofill® cost?
Nucleofill® is priced at £250 for 1.5ml or £450 for 3ml.
How much does Nucleofill® Eyes cost?
A single Nucleofill® Eyes session is £350.
Is the treatment painful?
Most clients experience manageable discomfort from the injections. Fine needles are used and appropriate comfort measures can be discussed during your consultation.
Is there any downtime?
Downtime is generally minimal. Small injection-site bumps, redness, swelling or tenderness are common immediately following treatment and usually settle naturally.
Can I wear makeup after treatment?
Your clinician will advise you when it is appropriate to apply makeup. It is important to follow the recommended post-treatment skincare guidance while the injection sites settle.
Can polynucleotides be combined with other treatments?
Potentially, yes. Polynucleotides can form part of a broader skin rejuvenation programme. However, treatment timing is important when combining procedures, so your clinician will advise on an appropriate treatment schedule.
Are polynucleotides suitable for everyone?
Not necessarily. Suitability depends on your skin condition, concerns, medical history and individual circumstances. A consultation is required before treatment.
Are there any risks?
As with any injectable treatment, temporary redness, swelling, tenderness, bruising or injection-site reactions can occur. More significant complications are possible, although uncommon. Your clinician will discuss the potential risks and benefits before treatment.
Will polynucleotides change my facial shape?
No. Polynucleotides are primarily designed to improve skin quality rather than add significant volume or alter facial contours.
Are polynucleotide results permanent?
No. The natural ageing process continues after treatment. Maintenance treatments may be recommended to support the improvements achieved.
Is a polynucleotide treatment right for me?
If your priority is improving skin quality, hydration, elasticity, firmness or fine lines without adding traditional filler volume, polynucleotides may be an option worth considering. Your clinician can assess your skin and recommend the most appropriate treatment for you.
Get in touch today
To get in touch with Mira, you can call +44 7423 245544 or book your appointment online.
Send Your Enquiry Today
- mira@storyaesthetics.uk
- 1 Lower Grosvenor Pl, London SW1W 0EJ, United Kingdom
- +44 7423 245544
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- Monday - Sunday, 10am - 8pm, by appointment only
Send Your Enquiry Today
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